MyBioSource.com's RNLS Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot. The RNLS Antibody was generated using RNLS as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Catalyzes the oxidation of the less abundant 1, 2-dihydro-beta-NAD(P) and 1, 6-dihydro-beta-NAD(P) to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Similarity: Belongs to the renalase family